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Diphtheria
Diphtheria. Diphtheria is an acute, toxin-mediated disease caused by. Corynebacterium diphtheriae. The name of the disease is derived. from the Greek diphthera, meaning leather hide. The disease was. described in the 5th Century B.C.


eMedicine - Diphtheria : Article by Malini K Singh, MD
... Diphtheria toxin is produced only by strains of C diphtheriae that are lysogenized with ... neuritis and myocarditis. The diphtheria toxin also causes local tissue destruction at ...


Diphtheria
Diphtheria. © 2002 Kenneth Todar University of Wisconsin-Madison Department of Bacteriology. Diphtheria. Corynebacteria are Gram-positive, aerobic, nonmotile, rod-shaped bacteria related to the Actinomycetes. ... bacterial interactions, have been made studying diphtheria and the diphtheria toxin ... U.S., demonstrated that diphtheria toxin neutralized by antitoxin (forming a Toxin-Anti-Toxin ...


Pfam 16.0 : Diphtheria_R
Diphtheria_R. Figure 1: 1ddt. Toxin. Accession number: PF01324. Diphtheria toxin, R domain ... The crystal structure of the diphtheria toxin homodimer has been determined to 2.5A resolution MEDLINE ... domains together constitute fragment B. Diphtheria toxin (EC:2.4.2.36) is a ...


eMedicine - Diphtheria : Article by Cem S Demirci, MD
... children, toxin-mediated disease, mitis diphtheria, gravis diphtheria, intermedius diphtheria, diphtheroids, coryneform ... contain antibodies to diphtheria toxin; their use for ...


diphtheria
DIPHTHERIA. The winter of 1925 was especially hard in Alaska with sub-freezing temperatures and what seemed like constant blizzards. The village of Nome was enduring the winter when two children suddenly contracted diphtheria. ... 1909 Theobald Smith demonstrated that diphtheria toxin neutralized by antitoxin remained immunogenic ... measures the patient's serum antibodies to diphtheria toxin. It is helpful in ...


Diphtheria Toxin, A subunit, antibody
... Diphtheria Toxin, A subunit, antibody ... MoAb 8A4 reacts with free A subunits of Diphtheria toxin. It does not react with the whole Diphtheria toxin and free B ...


Diphtheria Toxin Repressor
Iron is essential in virtually all living organisms for a wide variety of cellular processes. ... of siderophores, as well as diphtheria toxin. The diphtheria toxin repressor (DtxR) plays a key role ... The native crystals of diphtheria toxin repressor diffract to 1.9 Ã… resolution ...


#150 Diphtheria Toxin Literature ver. 9/02
... DIPHTHERIA TOXIN, CRM MUTANT, and DIPHTHERIA TOXOID. Diphtheria toxin (DT), secreted by certain strains of Corynebacterium diphtheriae, catalyzes ...


Diphtheria Toxin (428-429)
Diphtheria Toxin (428-429) Corynebacterium diphtheriae with lysogenic phage carrying the tox gene. Inhibits protein synthesis in eucaryotic cells. Polypeptide A: active portion of toxin ... Polypeptide B: binding portion of toxin and transport across plasma membrane ...


Melanie Bennett's Diphtheria toxin page
Diphtheria Toxin. I worked on dimeric and monomeric Diphtheria toxin (DT) as a graduate student in David Eisenberg's lab at UCLA. Diphtheria toxin is secreted by a bacterium, and kills cells by a 3 step mechanism.


Diphtheria Toxin
... Diphtheria Toxin Catalyzed Hydrolysis of NAD+: Molecular Dynamics Study of Enzyme-Bound Substrate, Transition ... The mechanism of the diphtheria toxin-catalyzed hydrolysis of NAD+ was ...


Pfam 16.0 : Diphtheria_T
Diphtheria_T. Figure 1: 1mdt. Toxin. Accession number: PF02764. Diphtheria toxin, T domain. Central domain of diphtheria toxin is the translocation (T) domain. ... The crystal structure of the diphtheria toxin homodimer has been determined to 2.5A resolution MEDLINE ... domains together constitute fragment B. Diphtheria toxin (EC:2.4.2.36) is a ...


Diphtheria Toxin antibody [3B6 ] (ab8307) datasheet
Diphtheria Toxin antibody [3B6 ] (ab8307) datasheet


Diphtheria Toxin antibody [1H2] (ab8306) datasheet
Diphtheria Toxin antibody [1H2] (ab8306) datasheet


DOE Document - Mutant with diphtheria toxin receptor and acidification function but defective in entry of toxin
A mutant of Chinese hamster ovary cells, GE1, that is highly resistant to diphtheria toxin was isolated.^The mutant contains 50% ADP-ribosylatable elongation factor 2, but its protein synthesis was not inhibited by the toxin even at ... sup 125}I-labeled diphtheria toxin was associated with GE1 cells as well ...


Diphtheria toxin vaccines bearing a mutated R domain (US5917017)
... Mutations in Diphtheria Toxin Separate . . . Science 238:536-539. ( ... Reversion of recombinant toxoids: Mutations in diphtheria toxin . . . PNAS 89:6207-6209. ( ...


Diphtheria - DrGreene.com
... the bacteria entered and on whether or not diphtheria toxin has made it into the blood stream. If the diphtheria is limited to the nose, it begins as a ...


Diphtheria Facts
Diphtheria. Diphtheria is a very contagious and potentially life-threatening bacterial disease. Diphtheria usually attacks the throat and nose. In more serious cases, it can attack the heart and nerves. ... life-threatening complications. The diphtheria toxin can damage the heart muscles and ...


Diphtheria (Corynebacterium diphtheriae)
Diphtheria (Corynebacterium diphtheriae) Corynebacteria are Gram-positive, aerobic, nonmotile, rod-shaped bacteria related to the Actinomycetes. ... interactions, have been made studying diphtheria and the diphtheria toxin. ... U.S., demonstrated that diphtheria toxin neutralized by antitoxin (forming a Toxin-Anti-Toxin complex, TAT ...


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